If the severity of the injury wasn't enough (this is The Simpsons, after all) Nick delivers a twist on his famous line - "Bye, everybody!" Near the end of the show, Murphy, from the heavens above, plays this song with Lisa, before he hits his final resting place. ‘But no matter what they did, nothing helped. But later, in season 15's "Diatribe of a Mad Housewife," Monroe appears out of the blue at Marge Simpson's book signing. There will also be people who happen to die within a month of getting the vaccine, particularly when the vaccine rolls out to elderly general population, due to the simple law of large numbers and the fact that on any given month far more elderly people die than young people. I believe this show was about the death of Lisas favorite sax player, "Bleeding Gums Murphy". The Simpsons' showrunner, Al Jean, has since revealed that the falling chunk of glass in the Simpsons movie only knocked Dr. Nick out, and he went on to make a full recovery after the events of "Trappuccino.". "Round Springfield" is the episode in which "Bleeding Gums" Murphy dies of kidney failure. However, he … It’s impossible not to feel enormous sympathy and empathy Ms. Neckelmann. Certainly, the clinical trials for neither the Pfizer/BioNTech nor the Moderna COVID-19 vaccines detected any signal for ITP in the form of bleeding, low platelet counts, or the like within two months of vaccination. The voice of Bleeding Gums Murphy was provided by Ron Taylor , while his … ‘All the blood results came back normal except for the platelets which came back as zero,’ Heidi said. He used to laugh at the most inappropriate times." Unsurprisingly, the first line of treatment, however, is corticosteroids, ranging from oral prednisone in less severe cases to intravenous dexamethasone or methylprednisolone in more severe cases in which the platelet count is so low as to risk bleeding. This time it showed just one platelet. All the latest gaming news, game reviews and trailers. Other characters have been retired under tragic real-life circumstances, such as Edna Krabappel, who was retired after the passing of voice actress, Marcia Wallace, in 2013. Either way, platelet transfusions are not a long-term treatment for ITP, as they can only temporarily increase the number of functional platelets. As I mentioned above, ITP is an autoimmune condition that results in platelet destruction in the spleen. Nick!" I also have another prediction. Ever. Humans are, as I like to say, pattern-seeking creatures. Be that as it may, Ms. Neckelman’s post led to sensationalistic headlines, like this one from (who else?) Be that as it may, another later study noted that bleeding episodes were uncommon among these patients, that the ITP associated with MMR disappeared within a month in 74% patients and only persisted beyond 6 months in only 10%. Dr. Gorski's full information can be found here, along with information for patients. Treatment depends on the severity of bleeding and the platelet count. Since then, Dr. Nick has resumed his status as a recurring Simpsons character, last appearing in a late 2019 episode of season 31. Given that there were approximately 44,000 subjects in the Pfizer/BioNTech trial with not a single patient showing signs if ITP, we can reasonably conclude that, even if the Pfizer/BioNTech vaccine increases the risk of ITP or causes ITP, the risk must be very, very low. Once the gums recede, they cannot grow back. It originally aired on the Fox network in the United States on April 30, 1995. Having previously written for various sports and music outlets, Craig's interest soon turned to TV and film, where a steady upbringing of science fiction and comic books finally came into its own. Casting Star Wars Rebels Characters For Ahsoka’s Disney+ Show, The Simpsons Failed To Commit To Dr. Nick’s Movie Death, The Simpsons' Opening Sequence Had A Continuity Error For 20 Years, The Simpsons: Ned Flanders Church Plot Hole Explained, The Mandalorian: Rogue One Easter Egg Teases Saw Gerrera Myth, Is The Alienist: Angel Of Darkness A True Story? Dr. Gregory Michael, 56, an OB-GYN at Mount Sinai Medical Center in Miami Beach, died after suffering a hemorrhagic stroke apparently resulting from a lack of platelets. He would not eat for (2) days but he was drinking water profusly then throw it up. It’s my privilege to get to writing about the origins for The Simpsons version of BGM on behalf of Wookiee. Most Popular on TIME 1 For a small number of children, ITP doesn’t go away on its own and may require further medical or surgical treatment. As bad as I feel for her, I just wish that Ms. Neckelmann hadn’t in her grief leapt to the conclusion that it was definitely the COVID-19 vaccine that had caused her husband’s death from ITP and trumpeted his story as a warning to the world, so that his death wouldn’t be “in vain.” Her Facebook post handed the antivaccine movement and COVID-19 cranks a powerful propaganda weapon. Two of the most famous examples include Maude Flanders' darkly comedic death at a sports game, indirectly caused by Homer, and the demise of Bleeding Gums Murphy, Lisa's jazz inspiration. Occasional bleeding of the gums can … In 80 percent of children who have ITP, the platelet count returns to normal within 6 to 12 months. Three weeks ago, I wrote about how the roll out of COVID-19 vaccines under the FDA’s emergency use authorization (EUA) for the Pfizer/BioNTech and Moderna RNA-based vaccines would very likely result in a tsunami of confusion of correlation with causation to blame the vaccines on all manner of seeming “adverse events,” whether the adverse events were caused by the vaccine or not. There are also other drugs that can be used, non-steroid immunosuppressants such as mycophenolate mofetil and azathioprine, or even the chemotherapy agent vincristine. Bleeding Gums Murphy's Death + Lisa's and Murphy's final duo. That would imply that, even if there is such an association, it is far safer to get the vaccine than it is to take the risk of catching COVID-19 – and, again, this is just one story. Every general surgeon knows about ITP, because it is general surgeons who are called upon to do a splenectomy in patients whose ITP is refractory to other treatments. [The Simpsons] Bleeding Gums Murphy was a drug addict, and this eventually led to his death. Ultimately, Dr. Michael was diagnosed with ITP, and here’s what ultimately happened: After two weeks of infusions and experimental treatments that failed to raise Gregory’s platelet count, doctors decided they had no choice. However a spokesman cautioned: ‘We don’t believe at this time that there is any direct connection to the vaccine.’. I thought at first it was a bufo toad but nothing that I found on the internet says anything about a dog bleeding to death (from his mouth and annus) from a toad. It’s thus probably more likely than not that Dr. Michael’s diagnosis so soon after vaccination is a coincidence. It was also noted that severe bleeding due to ITP after COVID-19 infection was rare and that diagnosing ITP in the setting of COVID-19 infection is challenging due to the common incidence of clotting disorders and diffuse intravascular coagulation (DIC), which can also cause platelet depletion. Pfizer told DailyMail.com Wednesday that it was aware of Dr. Michael’s ‘highly unusual’ death and was investigating further. David H. Gorski, MD, PhD, FACS is a surgical oncologist at the Barbara Ann Karmanos Cancer Institute specializing in breast cancer surgery, where he also serves as the American College of Surgeons Committee on Cancer Liaison Physician as well as an Associate Professor of Surgery and member of the faculty of the Graduate Program in Cancer Biology at Wayne State University. Another tombstone of Bleeding Gums Murphy is seen in the opening sequence of THOH XXII. The first such story has started circulating in the antivaccine nooks and crannies of social media, but it’s also being flogged by the usual British tabloids. However, many dental treatments can help restore the gums around the teeth. Dr. Hibbert: "Hey I've got an older brother that I'll never see. Ron Taylor, Actor: Trading Places. National Center for Complementary and Integrative Health, Steven P. Novella, MD – Founder and Executive Editor, David H. Gorski, MD, PhD – Managing Editor, Topical Barley Flour for the Management of Newborn Jaundice: A Real Study Done by Actual Pediatricians, specific examples of syncope and Bell’s palsy, applies to claims that vaccines cause autism, first story of a death after vaccination against COVID-19, surgical oncologist at the Barbara Ann Karmanos Cancer Institute, American College of Surgeons Committee on Cancer Liaison Physician, bleeding from the gums (for example, during dental work), Viral infections (including chickenpox, parvovirus, hepatitis C, Epstein-Barr, and HIV), Sepsis, a severe bacterial infection in your blood, Certain drugs for heart problems, seizures, and infections, Heparin, a blood thinner used to prevent blood clots. Because of this, The Simpsons can bend its own rules and bring back the likes of Dr. Nick if the writers feel he would be a worthy comic addition to an episode. Despite being a reliable source of gags, the 2007 Simpsons movie appeared to kill off Dr. Nick. Here’s the first story of a death after vaccination against COVID-19 that sounds plausible on the surface that allows me to revisit this issue because, unlike the cases of people who are, for example, hit by a car within two weeks of vaccination, we can’t just dismiss it a priori: A Florida doctor has died several weeks after receiving a COVID-19 vaccine, although it’s not yet clear whether his death Monday was related to the shot he received on Dec. 18. But they said you cannot go home, this is incredibly dangerous, you could suffer a brain bleed and die.’. Directed by Wesley Archer. ). They gave him an incredible amount of platelet infusions, I’m told all the platelets in Miami Dade County,’ Heidi said. It’s always a pleasure to re-watch episodes of the Best. This brings us, after this long detour into the weeds of what ITP is, what can trigger it, and how it’s treated, back to the question of COVID-19 vaccination and ITP, the question at the heart of the sad story of Dr. Michael’s sudden development of ITP refractory to treatment that claimed his life within two weeks of diagnosis. But it can also point to other health problems. 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Splenectomy can result in durable remission of ITP in up to 80% of patients, but, again, it’s generally risky because of the elevated risk of bleeding in the sorts of patients for whom the operation is generally reserved, namely those with refractory severe ITP. However, some teenagers and children do get this type of ITP. Indeed, one of the deaths in the placebo group for the Pfizer vaccine was due to a hemorrhagic stroke. Bleeding Gums learned his musical skills "at the feet of Blind Willie Witherspoon". - Share your reason with the rest of the community. He died of a heart attack aged 49, on January 16, 2002, at his home in Los Angeles, California. Most often that bleeding takes the form of “petechiae”, or tiny bruise-like markings on the skin, but in rare cases ITP can lead to dangerously low numbers of platelets, levels at which the risk of spontaneous bleeding in the brain and other organs becomes very high. If you are a potential patient and found this page through a Google search, please check out Dr. Gorski's biographical information, disclaimers regarding his writings, and notice to patients here. While the Flanders family losing the matriarch of their house is devastating, her character is not the most memorable. Again, most symptoms other than the sort that I experienced will turn out not to be due to the vaccine. ‘He was in very good health. Murphy is voiced by Ron Taylor, possibly the first guest star in the series if not the first. She has lost weight and only drinks water. Again, you can’t tell that from just one case, however dramatic and tragic. Related: The Simpsons' Opening Sequence Had A Continuity Error For 20 Years, A year or so later, however, Dr. Nick is miraculously resurrected in The Simpsons season 20. The Daily Mail: Heidi Neckelmann says obstetrician Gregory Michael, 56 – her ‘best friend’ and partner of 28 years – was active, healthy and had no pre-existing conditions before getting the jab on December 18. Dr. Nick's revival isn't an isolated case in The Simpsons. In cases of refractory ITP, thrombopoietin receptor agonists (drugs that stimulate the receptor) can stimulate the bone marrow to make more platelets. … bleeding Gums Murphy was a deep sea fisherman blood from an artery bleeds the... 'S and Murphy 's final duo Clown and is given a $ 100,000 settlement of Wookiee a mistake was! Trading Places ( 1983 ), a monoclonal antibody against the protein CD20, which was lucrative..., Yeardley Smith sad to learn that bleeding Gums Murphy is seen in the Simpsons soon after vaccination later ). Blood cancers and autoimmune diseases a much more noticeable incidence of ITP that high should produce a much noticeable! 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